Table 1.
Demographic, clinical, and laboratory features of healthy subjects and Rtx patients
| Parameters | Healthy subjects (n = 19) | Rtx patients (n = 29) | p | ρ(p)1 |
|---|---|---|---|---|
| Age, years | 36.9 ± 8.9 | 40.1 ± 11.9 | 0.33 | 0.29 (0.05) |
| Male/female, n | 10/9 | 17/12 | 0.80 | – |
| BMI | 26.7 ± 4.3 | 25.0 ± 3.9 | 0.18 | – |
| SBP, mm Hg | 133 ± 9 | 124 ± 31 | 0.56 | – |
| DBP, mm Hg | 83 ± 8 | 85 ± 14 | 0.94 | – |
| Hemoglobin, g/dl | 13.8 ± 0.9 | 13.6 ± 1.8 | 0.87 | – |
| Glucose, mg/dl | 92.3 ± 8.2 | 110 ± 38.9 | 0.10 | – |
| Urea, mg/dl | 27.2 ± 8.22 | 41.8 ± 28 | 0.005 | – |
| Creatinine, mg/dl | 0.7 ± 0.15 | 1.4 ± 0.6 | <0.0001 | 0.66 (<0.0001) |
| Albumin, g/dl | 4.4 ± 0.2 | 4.3 ± 0.3 | 0.27 | −0.19 (0.20) |
| Uric acid, mg/dl | 3.9 ± 0.7 | 5.7 ± 1.5 | <0.0001 | 0.60 (<0.0001) |
| AST, IU/l | 22 ± 9 | 22 ± 6 | 0.60 | – |
| ALT, IU/l | 21 ± 17 | 24 ± 9 | 0.70 | – |
| LDL-C, mg/dl | 124 ± 27 | 108 ± 34 | 0.16 | 0.06 (0.69) |
| HDL-C, mg/dl | 47 ± 13 | 46 ± 13 | 0.85 | 0.05 (0.7) |
| Triglyceride, mg/dl | 104 ± 36.7 | 185 ± 84.8 | 0.001 | 0.37 (0.01) |
| Calcium, mg/dl | 8.8 ± 0.58 | 9.6 ± 0.67 | 0.001 | – |
| Phosphorus, mg/dl | 3.0 ± 0.4 | 3.0 ± 0.86 | 0.65 | – |
| eGFR, ml/min | 121.2 828.3 | 62.6 ± 24.2 | <0.0001 | −0.69 (<0.0001) |
| hs-CRP, mg/l | 2.8 (2.0–3.6) | 8.4 (4.15–12.8) | <0.0001 | 0.64 (<0.0001) |
| Spot urine protein-to-creatinine ratio, g/mg | 0.09 ± 0.1 | 0.3 ± 0.4 | 0.004 | 0.50 (0.001) |
| PTX, ng/ml | 2.3 (2.1–2.5) | 5.2 (4.45–6.30) | <0.0001 | 0.68 (<0.0001) |
| Neutrophils, mm3 | 3,213 ± 720 | 5,429 82,173 | <0.0001 | |
| Lymphocytes, mm3 | 2,409 ± 742 | 2,201 ± 691 | 0.48 | |
| NLR | 1.28 ± 0.33 | 2.6 ± 1.31 | <0.0001 | 0.64 (<0.0001) |
| CIMT, mm | 0.4 ± 0.08 | 0.75 ± 0.20 | <0.0001 | – |
Values are means ± SD or medians (interquartile range), unless otherwise indicated. ALT = Alanine aminotransferase; AST = aspartate aminotransferase; DBP = diastolic blood pressure; SBP = systolic blood pressure.
1
Spearman rank univariate analysis for CIMT.