TABLE 4.

Phases of hepatitis B virus (HBV) infection

Phases	HBsAg	HBeAg	Anti-HBe	ALT pattern	HBV DNA
Immune tolerant	Positive	Positive	Negative	Normal	∼ >2×104 to >2×108 IU/mL
Immune clearance	Positive	Positive	Negative	Normal or elevated	∼ >2×104 to >2×108 IU/mL
Inactive disease	Positive	Negative	Positive	Normal	<200 IU/mL
HBeAg-negative chronic hepatitis	Positive	Negative	Positive	Normal or elevated	Undetectable to >2×108 IU/mL
Resolution of infection	Negative	Negative	Positive	Normal	Undetectable

ALT Alanine aminotransferase; Anti-HBe Hepatitis B e antibody; HBeAg Hepatitis B e antigen; HBsAg Hepatitis B surface antigen