Figure 3.
Examples of topological variations for Trx-fold SFs. Red: Trx-fold, Green: inserts or domain pairing additions to the Trx fold. A. Human Trx (PDB 1AUC). B. Human Prx V (PDB 1HD2). C. E. coli disulfide binding protein A (PDB 1FVK). D. Human glutathione transferase M2-2 (PDB 1XW5). E. Yeast protein disulfide isomerase (PDB 2B53).