Table I. P2X7 function is independent of asthma risk factors.
Subject characteristics were stratified by P2X7 function.
| P2X7 pore function | |||
|---|---|---|---|
| Birth and year 1 risk factors | Low (n = 48) |
Normal (n = 124) |
P value |
| Maternal asthma ever | 37% | 38% | 0.90 |
| Paternal asthma ever | 28% | 34% | 0.49 |
| Smoke exposure in year 1 | 27% | 24% | 0.69 |
| Day care attendance in year 1 | 50% | 50% | 1.00 |
| Exclusive breastfeeding during first 6 months | 38% | 35% | 0.73 |
| Dog in home at birth | 40% | 33% | 0.42 |
| Cat in home at birth | 27% | 32% | 0.51 |
| Older siblings | 54% | 57% | 0.71 |
| Active atopic dermatitis in year 1 | 30% | 26% | 0.59 |
| Birth month | -- | -- | 0.62 |
| Birth weight ± st dev (oz) | 123 ± 16 | 125 ± 19 | 0.96 |
| Male gender | 60% | 56% | 0.64 |