Table 1.
Results from relative-rate tests based on nucleotide single-gene alignments and mt and nuclear nucleotide data sets
| |
Mean weighted substitution rates |
Probability of relative-rate tests |
||||||
|---|---|---|---|---|---|---|---|---|
| gene | K1 | K2 | K3 | K4 | p (1 vs. 2) p < 0.05 | p (1 vs. 3) p < 0.0167 | p (1 vs. 4) p < 0.0167 | p (3 vs. 4) p < 0.0167 |
|
atp6 |
0.427863 |
0.473377 |
0.481832 |
0.455958 |
0.014730* |
0.005722* |
0.105996 |
0.139169 |
|
atp8 |
0.548420 |
0.597954 |
0.603741 |
0.598698 |
0.262944 |
0.238598 |
0.273487 |
0.916317 |
|
cob |
0.357846 |
0.395422 |
0.400600 |
0.376129 |
0.153630 |
0.127295 |
0.461317 |
0.438624 |
|
cox1 |
0.258230 |
0.291037 |
0.294927 |
0.288984 |
1.26·10-4* |
4.86·10-5* |
4.59·10-5* |
0.475097 |
|
cox2 |
0.279140 |
0.349751 |
0.355794 |
0.328478 |
6.31·10-6* |
3.76·10-6* |
5.41·10-4* |
0.068572 |
|
cox3 |
0.289143 |
0.322240 |
0.328289 |
0.304404 |
0.007560* |
0.002549* |
0.170152 |
0.046288 |
|
nad1 |
0.371027 |
0.401329 |
0.413424 |
0.383640 |
0.023124* |
0.002486* |
0.296321 |
0.020798 |
|
nad2 |
0.507982 |
0.547513 |
0.548407 |
0.525736 |
0.025438* |
0.026856 |
0.251499 |
0.170942 |
|
nad3 |
0.434548 |
0.430927 |
0.434119 |
0.433411 |
0.869559 |
0.985402 |
0.956541 |
0.974496 |
|
nad4 |
0.431683 |
0.557581 |
0.560891 |
0.590991 |
1.00·10-7* |
1.00·10-7* |
1.00·10-7* |
0.050825 |
|
nad4L |
0.497599 |
0.631415 |
0.643682 |
0.588595 |
8.27·10-4* |
6.30·10-4* |
0.009870* |
0.150316 |
|
nad5 |
0.411432 |
0.519950 |
0.517924 |
0.538763 |
1.00·10-7* |
1.00·10-7* |
1.00·10-7* |
0.081618 |
|
nad6 |
0.463362 |
0.505592 |
0.512071 |
0.518343 |
0.088626 |
0.056897 |
0.026638 |
0.765287 |
|
rrnS |
0.191816 |
0.26154 |
0.265755 |
0.253359 |
1.00·10-7* |
1.00·10-7* |
9,73·10-3* |
0.267807 |
|
rrnL |
0.193460 |
0.217439 |
0.219738 |
0.214547 |
0.005620* |
0.003273* |
0.0176213 |
0.516844 |
| tRNAs |
0.272203 |
0.309978 |
0.312829 |
0.299828 |
0.001434* |
0.000809* |
0.010368* |
0.221773 |
|
all mt genes |
0.330116 |
0.379173 |
0.384017 |
0.372441 |
1.00·10-7* |
1.00·10-7* |
1.00·10-7* |
0.001898* |
|
bdnf |
0.162298 |
0.183220 |
0.183143 |
0.188813 |
0.063971 |
0.066639 |
0.019606 |
0.425053 |
|
cxcr4 |
0.305898 |
0.310540 |
0.310616 |
0.317277 |
0.749761 |
0.760622 |
0.463425 |
0.635922 |
|
h3a |
0.072185 |
0.071813 |
0.074309 |
0.069597 |
0.967280 |
0.831715 |
0.787527 |
0.662899 |
|
pomc |
0.383197 |
0.374114 |
0.370759 |
0.381447 |
0.747452 |
0.671607 |
0.956266 |
0.667038 |
|
rag1 |
0.278115 |
0.298226 |
0.297262 |
0.300048 |
0.177027 |
0.210499 |
0.172426 |
0.837948 |
|
rag2 |
0.436022 |
0.493728 |
0.494946 |
0.512607 |
0.002539* |
0.003285* |
2.38·10-4* |
0.314455 |
|
rho |
0.177431 |
0.164405 |
0.167539 |
0.177528 |
0.444978 |
0.596616 |
0.995982 |
0.609647 |
|
slc8a1 |
0.236296 |
0.253733 |
0.253592 |
0.255299 |
0.029208* |
0.041528 |
0.030535 |
0.840326 |
|
slc8a3 |
0.223439 |
0.233366 |
0.232416 |
0.238298 |
0.280968 |
0.356872 |
0.115003 |
0.460431 |
| all nuc genes | 0.067158 | 0.075283 | 0.074880 | 0.072843 | 0.036588* | 0.055309 | 0.164760 | 0.607197 |
K values are mean weighted substitution rates for (1) non-neobatrachians, (2) all neobatrachians, (3), species-poor neobatrachians (Heleophrynidae, Calyptocephalellidae, Limnodynastidae, Sooglossoidea), and (4) species-rich neobatrachians (Ranoides and Nobleobatrachia). Probabilities (p) of relative-rate tests correspond to the comparisons between the different groups (shown in parentheses). Statistically significant results (p < 0.05; or p < 0.05/3 = 0.0167 to correct for multiple testing) are in bold italics and marked with an asterisk. Abbreviations of mt genes follow [44]; see main text for full names of nuclear genes.