Table 3.
Comparison of the results obtained with each treatment during the hospitalizations
| Variables | Erythromycin | Neomycin | p |
|---|---|---|---|
| ∆ IHD1 |
3.00 (2.25 : 4.00) |
5.00 (3.25 : 11.25) |
0.032 |
| ∆ GCS 1 |
1.00 (0.25 : 2.00) |
0.00 (0.00 : 3.25) |
0.394 |
| ∆ MELD 2 |
−0.55 ± 1.53 |
−0.62 ± 2.08 |
0.917 |
| ∆ HEG 1 |
2 (1 : 2.5) |
2 (1 : 3) |
0.806 |
| ∆ HEI 1 |
−6.00 (−9.00 : -1.50) |
−5.00 (−7.00 : -1.25) |
0.632 |
| ∆ CRP 1 |
0.30 (0.10 : 0.70) |
1.10 (0.15 : 4.30) |
0.111 |
| ∆ NH32 |
−31.40 ± 49.32 |
−30.70 ± 92.15 |
0.979 |
| ∆ ALT2 |
−3.20 ± 8.54 |
3.71 ± 7.12 |
0.026 |
| ∆ AST 2 |
−15.70 ± 48.06 |
8.42 ± 21.80 |
0.678 |
| ∆ AP 2 |
−17.70 ± 65.3 |
−12.30 ± 48.90 |
0.802 |
| ∆ GGT 1 |
−7.00 (−29.00 : 0.75) |
−5.00 (−25.50 : 5.00) |
0.724 |
| ∆ urea 2 |
−2.19 ± 20.64 |
−4.25 ± 23.72 |
0.802 |
| ∆ creatinine 2 | −0.10 ± 0.27 | −0.20 ± 0.30 | 0.289 |
1 median, 1º : 3º quartiles ; Mann–Whitney test comparison.
2 mean ± standard deviation ; t test comparison.
∆ = final – initial values. IHD = in-hospital days. GCS = Glasgow coma scale. HEI = hepatic encephalopathy index. HEG = hepatic encephalopathy grade. CRP = C reactive protein (mg/dl). NH3 = serum ammonia (μM/l). ALT = alanine aminotranspherase, AST = aspartate aminotranspherase, AP = alcaline phosphatase, and GGT = gamma-glutamyltranspeptidase (all in U/l). Urea and creatinine are measured in mg/dl.