Table 5.

Summary of parameter distributions for costs (in 2010 euros) used in the PSA

Costs of resources	Parameter	Expected costs (€) (standard error)
		After THR		After TKR
		Hospital perspective	SHI perspective	Hospital perspective	SHI perspective
Prophylaxis costs with enoxaparin in the case of
Post-discharge VTE or no VTE and no MB	par_14	0	106.42 (10.64)	0	1.63 (0.16)
Prophylaxis costs with rivaroxaban in the case of
MB with or without VTE	par_15	13.00 (1.30)	0	13.00 (1.30)	0
Pre-discharge VTE without MB	par_16	18.20 (1.82)	0	18.20 (1.82)	0
Post-discharge VTE or no VTE and no MB	par_17	32.24 (3.22)	134.85 (13.49)	33.02 (3.30)	2.06 (0.21)
Total costs of pre-discharge VTE
DVT	par_18	1,282.27 (128.33)	157.35 (17.74)	1,115.14 (111.51)	157.40 (15.74)
Non-fatal PE	par_19	2,105.22 (210.52)	157.23 (15.73)	2,362.79 (236.28)	348.40 (34.84)
Total costs of post-discharge VTE
DVT	par_20	0	1,995.89 (199.59)	0	1,995.89 (199.59)
Non-fatal PE	par_21	0	3,700.43 (370.04)	0	3,700.43 (370.04)
Fatal PE	par_22	0	1,256.43 (125.64)	0	1,256.43 (125.64)

PSA = probabilistic sensitivity analysis, THR = total hip replacement, TKR = total knee replacement, SHI = social health insurance, VTE = venous thromboembolism, MB = major bleeding, DVT = deep vein thrombosis, PE = pulmonary embolism.