Figure 6. Oncolytic potential of Ad5T122 and Ad5 in a lung cancer xenograft model.
Mice were treated with 107 PFU of Ad5, Ad5T122, or injected with a corresponding volume of PBS (Mock) on days 0, 2 and 4, as indicated by arrows. Tumour size was calculated as the volume of an ellipsoid. Tumour growth is expressed as a percentage increase from first day of virus injection. The asterisks (*) indicate a statistically significant differences in the volumes of the PBS-injected tumours compared to the virus-treated tumours. The number of tumours in each group were 10 (PBS), 11 (Ad5T122), and 12 (Ad5). Data are presented as mean ± standard error.