Table 1.
Demographic data and scores on neuropsychological tests
| |
Diagnostic category |
|||
|---|---|---|---|---|
| NC n=249 | aMCI n=134 | AD n=97 | All type of dementia n=161 | |
| Age |
67.08(8.33) |
69.89(8.23) ** |
71.08(8.43) ** |
71.0893(8.43) ** |
| Education |
12.89(3.30) |
11.32(3.84) ** |
10.62(4.49) ** |
10.55(4.39) ** |
| Sex(female/male) |
158/91 |
76/58 |
54/43 |
81/80 |
| Race(Han/others) |
240/9 |
126/7 |
93/3 |
153/7 |
| MMSE |
28.41(1.50) |
26.98(2.04) ** |
15.69(5.91) **△△ |
16.28(6.06)**△△ |
| HVLT |
|
|
|
|
| Trail 1 |
5.91(1.90) |
4.48(1.69) ** |
1.46(1.81) **△△ |
1.57(1.76) **△△ |
| Trail 2 |
8.54(2.05) |
6.48(2.15) ** |
2.28(2.27) **△△ |
2.41(2.22) **△△ |
| Trail 3 |
9.63(1.91) |
7.21(2.65) ** |
2.55(2.59) **△△ |
2.71(2.45) **△△ |
| Total learning |
23.76(5.66) |
18.04(5.93) ** |
6.09(6.23) **△△ |
6.37(5.91) **△△ |
| Recognition |
11.29(1.23) |
10.32(2.18) ** |
3.42(5.38) **△△ |
3.95(5.52) **△△ |
| HVLT total score |
35.34(5.59) |
28.49(6.67) ** |
9.65(10.54) **△△ |
10.54(10.19)**△△ |
| HVLT total score/MMSE ratio |
1.23(0.23) |
1.05(0.26) |
0.46(0.60) |
0.50(0.56) |
| HAMD | 3.78(3.30) | 3.84(3.12) ** | 2.42(2.12) **△△ | 2.78(2.47) **△△ |
Notes: Data are presented as mean (standard deviation); NC = normal cognition; aMCI = amnestic mild cognitive impairment; AD = Alzheimer’s disease; MMSE = Mini-mental state examination; HVLT = Hopkins verbal learning test; HAMD = Hamilton Depression scale;**p < 0.001 compared to NC; p < 0.001 compared to aMCI.