Figure 6. Effect of SLRef RNA on HCV IRES mediated translation in vivo in BALB/c mice. (A) Relative Luciferase activity of Huh7 cells harvested 24 h post transfection of F-virosome co-entrapped with HCV bicistronic construct and plasmid DNAs encoding either SLRef or NSP RNA. (B) Relative luciferase activities of liver parenchymal cells from BALB/c mice injected i.v. with F-virosomes loaded with the HCV bicistronic constructs along with the plasmid DNAs encoding either SLRef or NSP RNA.