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. 2013 Jan 22;8(1):e54866. doi: 10.1371/journal.pone.0054866

Figure 11. Promoted downregulation of CD81 surface level by enhancing HCV replication.

Figure 11

Huh7 cells were mock transfected or transfected with JFH1 or J6/JFH1 viral RNA (A), or mock transfected or transfected with JFH1 or JFH1 AM120 adaptive mutant viral RNA (B). At day 3 posttransfection, the cells were analyzed for protein expressions (left panel), CD81 surface expression (middle panel), and H77-HCVpp and JFH1-HCVpp infection (right panels). Data represents mean ± SEM (n = 3).