Table 5. Stage Two NCK2 SNP rs2033008 Allele Frequencies in Japanese POAG, NTG and Controls Subjects.
Allele frequency | Genotype | |||||||
T | A | Odds ratio (CI) | p value* | T/T | T/A | A/A | p value** | |
POAG | 0.703 | 0.297 | 0.87 (0.65–1.16) | 0.35 | 89/187 | 85/187 | 13/187 | 0.069 |
NTG | 0.750 | 0.250 | 0.69 (0.53–0.89) | 0.0053 | 159/286 | 111/286 | 16/286 | 0.0056 |
Control | 0.673 | 0.327 | 130/271 | 105/271 | 36/271 |
Fisher's exact test,
Chi-square test.
A/A is mutant homozygote, T/A is heterozygote, and T/T is wild homozygote.