Table 2. Univariate and multivariate association between alleles for SNPs-43 and -44 in CAPN-10 and Log-beta cell function (%) in non-diabetic and diabetic subjects.

				Adjusted by
				arsenic in urine		arsenic in urine, age, sex and BMI
		ß coefficient	p	ß coefficient	p	ß coefficient	p
Non-diabetic subjects	SNP-43
	G/A vs A/A	−0.34	0.226	−0.28	0.302	−0.09	0.748
	G/G vs A/A	−0.57	0.037*	−0.49	0.073	−0.32	0.278
	P for trend		0.024*		0.050		0.128
	SNP-44
	C/T vs T/T	−0.43	0.022*	−0.44	0.014*	−0.38	0.028*
Type 2 diabetic subjects	SNP-43
	G/A vs A/A	−0.02	0.964	−0.05	0.912	0.14	0.763
	G/G vs A/A	0.05	0.914	−0.01	0.989	0.12	0.814
	P for trend		0.871		0.978		0.874
	SNP-44
	C/T vs T/T	0.47	0.211	0.56	0.156	0.57	0.160

ß coefficients refer to the estimated change in Log-transformed beta-cell function (%) values between each allele. Symbol denotes statistical significance p<0.05 (*).