Table 3. Brain activation across extinction.
| KE | T | Region | |
| PG within group analysis (First CS >Last CS) | |||
| Whole brain analysis | 826 | 5.61 | R lateral amygdala |
| 582 | 3.48 | Hypothalamus | |
| Lateral amygdala mask | 147 | 3.35 | R lateral amygdala* |
| PG within group analysis (Last CS> First CS) | |||
| Whole brain analysis | 661 | 5 | Thalamus (extending to central amygdala) |
| 1589 | 4.19 | Sensory cortex | |
| 1242 | 3.7 | Ventral subiculum, midbrain | |
| 444 | 3.09 | Ventral pallidum | |
| Between Group Analysis | |||
| PG>UG (First CS>Last CS) | |||
| Whole brain analysis | 1211 | 4.21 | Sensory cortex |
| 485 | 4.11 | R lateral amygdala | |
| 1295 | 3.99 | Granular insular cortex | |
| 825 | 3.26 | Hypothalamus | |
| Lateral amygdala mask | 91 | 3.35 | R lateral amygdala* |
| PG>UG (Last CS> First CS) | |||
| 1542 | 3.97 | RSG | |
| 1221 | 3.9 | Ventral subiculum includes medial geniculate nucleus | |
| 457 | 3.89 | Thalamus | |
Significant regional brain activation (BOLD responses) to the first CS presentation compared to last CS presentation and the reverse. PG = paired group, UG = unpaired group. KE = cluster extent in voxels. T = peak voxel t-statistic. Clusters reaching P corrected <0.05 are shown.* = significant (P corrected <0.05) within lateral amygdala ROI. R = right, L = left, RSG = retrospenial granular cortex. PG, n = 14; UG, n = 10.