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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Mol Cancer Res. 2012 Nov 16;11(1):86–94. doi: 10.1158/1541-7786.MCR-12-0243-T

Figure 1. DARPP-32 increased invasive activity in gastric cancer cells.

Figure 1

A) Invasion assays were performed using the matrigel-boyden chamber assay. AGS cells lentiviral expressing DARPP-32 (DP32) are more invasive than control (ctrl). B) The quantification demonstrates a significant increase in the number of invasive cells in AGS cells stably expressing DARPP-32 (p<0.01). Western blot demonstrates the levels of DARPP-32. C–D) The knockdown of DARPP-32 in the MKN-45 cells (shRNA01 and 02) led to a significant reduction in cell invasion (p<0.01). The levels of DARPP-32 are shown by Western blot analysis.