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ETC Loci as Insulators and Chromosome Organizers
| Organism | # of ETC sites | Genomic context | Genome Organization | Insulator Activity |
|---|---|---|---|---|
| Budding yeast | ~9 | Divergent genes | Peripheral tethering | Barrier activity UAS blocking activity |
| Fission yeast | ~60 | Divergent genes | Adjacent to centromeres | Barrier activity |
| Mammals | ~1800 | Pol-II TSS Not clustered along chromosome | Unknown | No barrier activity |
