Table 2.
Differences in miRNAprofiles between single dose and multi-fraction radiation. Table summarizes pathway analysis of previously reported microRNAs, following exposure to SD and MF radiation.
| Cell type | Radiation Protocol | Functional Categories | Type of Analysis | Ref | |
|---|---|---|---|---|---|
| LNCaP | MF | 0.5Gy ×10 | Genetic disorder, skeletal and muscular disorders, inflammatory disease | in vitro, miRNA | John-Aryankala yil, et al. (2012) |
| 1Gy ×10 | Reproductive system disease, genetic disorder, skeletal and muscular disorder | ||||
| SD | 5Gy ×1 | Cell cvcle cellular orowtli and proliferation cellular development | in vitro, miRNA | ||
| 10Gy ×1 | Cellular development, cellular growth and proliferation, cell cycle | ||||
|
| |||||
| PC3 | MF | 0.5Gy ×10 | Cell death, liver necrosis/cell death, cell cycle | in vitro, miRNA | |
| 1Gy ×10 | Reproductive system disease, genetic disorder, skeletal and muscular disorders | ||||
| SD | 5Gy ×1 | Cellular development, embryonic development, nervous system development and function | in vitro, miRNA | ||
| 10Gy ×1 | Cellular assembly and organization, cell death, skeletal and muscular system development and function | ||||
|
| |||||
| DU145 | MF | 0.5Gy ×10 | Cell cycle, cell death, cell morphology | in vitro, miRNA | |
| 1Gy ×10 | DNA replication, recombination and repair, cell death, liver necrosis/cell death, inflammatory response, antigen presentation, cell-to-cell signaling and interaction | ||||
| SD | 5Gy ×1 | None | in vitro, miRNA | ||
| 10Gy ×1 | Cell cycle, cell death, cell morphology | ||||