Table 4.
Association of HNSCC with smokeless tobacco among never cigarette smokers.
| Variables | Control | Case | OR1 | 95% CI1 | OR2 | 95% CI2 |
|---|---|---|---|---|---|---|
| Smokeless tobacco use status | ||||||
| Never | 490 | 241 | 1.00 | --- | 1.00 | --- |
| ≥ 20 times | 3 | 7 | 5.05 | 1.27, 20.05 | 4.21 | 1.01, 17.57 |
| Duration of smokeless tobacco use in lifetime (y) | ||||||
| Never | 490 | 241 | 1.00 | --- | 1.00 | --- |
| > 0 to < 10 | 5 | 2 | 0.87 | 0.17, 4.58 | 0.78 | 0.15, 4.13 |
| ≥ 10 | 1 | 7 | 15.21 | 1.84, 125.81 | 13.21 | 1.53, 114.46 |
| p for trend | 0.011 | 0.018 | ||||
| Average frequency of smokeless tobacco use per week (times) | ||||||
| Never | 490 | 241 | 1.00 | --- | 1.00 | --- |
| > 0 to < 7 | 5 | 5 | 2.17 | 0.61, 7.70 | 1.94 | 0.54, 7.03 |
| ≥ 7 | 1 | 3 | 6.50 | 0.67, 63.50 | 5.11 | 0.47, 55.94 |
| p for trend | 0.083 | 0.142 | ||||
| Lifetime numbers of smokeless tobacco use (times/wk*y) | ||||||
| Never | 490 | 241 | 1.00 | --- | 1.00 | --- |
| > 0 to < 20 | 5 | 3 | 1.30 | 0.30, 5.58 | 1.22 | 0.29, 5.26 |
| ≥ 20 | 1 | 5 | 10.85 | 1.25, 94.32 | 9.15 | 0.97, 86.59 |
| p for trend | 0.031 | 0.053 | ||||
1
OR adjusted for age and gender
2
OR adjusted for age, gender, race (White, non-White), education (3 categories), smoking (continuous), ever smoker, alcohol drinking (continuous)