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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Neurogastroenterol Motil. 2013 Jan 2;25(2):e101–e113. doi: 10.1111/nmo.12059

Figure 6.

Figure 6

L-Methionine blocks membrane hyperpolarization and reduction in AP complexes in response to stretch. (A) Under control conditions, application of the stretch ramp led to hyperpolarization in membrane potential (dashed line) and loss of spontaneous AP complexes and phasic contractions. (B) In the presence of L-methionine (1 mM), AP complexes and associated phasic contractions were more pronounced (B). Application of the 5 mN stretch ramp in the presence of L-methionine blocked membrane hyperpolarization (dashed line) and did not lead to loss of spontaneous contractions.