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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Biomed Chromatogr. 2012 Oct 5;27(4):422–432. doi: 10.1002/bmc.2809

Table 5.

Endogenous concentration of target oxidized LA metabolites (OXLAMs) measured by method of one-point standard addition and standard addition curve extrapolation and ratio of plasma levels of OXLAMs to precursor LA

Compound One-point standard addition Standard addition curve extrapolation
Mean ± SD (nmole/L) Ratio of OXLAMs/unesterified LA* (nmol/μmol) (nmole/L)
9-HODE 57.9 ± 18.7 1.0 ± 0.3 84.0
13-HODE 123.2 ± 31.1 2.1 ± 0.5 138.6
9-oxoODE 218.1 ± 53.7 3.8 ± 0.9 263.0
13-oxoODE 57.8 ± 19.2 1.0 ± 0.3 69.5
Total OXLAMs 456.7 ± 76.4 7.9 ± 1.3 555.1
*

: the plasma concentrations of unesterified linoleic acid, esterified linoleic acid, and total linoleic acid were 59.7, 1514.3 and 1574.0 μM/L, respectively, which were determined by GC.