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. Author manuscript; available in PMC: 2013 Jan 23.
Published in final edited form as: Pediatr Crit Care Med. 2010 Jan;11(1):109–116. doi: 10.1097/PCC.0b013e3181b01042

Figure 1.

Figure 1

Pharmacologic induction and maintenance of hypothermia. Juvenile (4 wk) C57BL/6 mice were given lipopolysaccharide 1 μg/g IP followed by chlorpromazine 15 μg/g IP, then placed in incubators preset to 28°C or 32°C air temperature to maintain rectal temperatures at approximately 32°C or 37°C. Rectal temperature was monitored continuously in one mouse in each group of three and checked every 30 mins in the other mice. Adjustments in incubator temperature were made to maintain rectal temperatures in the target range. Data points represent mean rectal temperature ± SD at 30-min intervals for 14 mice in each temperature group.