Figure 3. Principal Component Analysis of LCMS data from the mucosal M-SHIME samples after colonization with microbiota derived from either healthy subjects (○) or UC patients in relapse (Δ).

Score (left) and loading (right) plots are shown. PC1 and PC2 explain 29.1% and18.6% of the variance, respectively. Numbers from 1to 10 in the loading plot correspond to metabolite candidates enriched in the M-SHIME mucin-coveres microcosms. Masses of the candidates are given in Table 4.