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. 2013 Jan 22;104(2):496–504. doi: 10.1016/j.bpj.2012.12.004

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© 2013 by the Biophysical Society.

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State diagrams for the actomyosin ATPase model. A, actin; M, myosin; TRPN, troponin; f_x and g_x, transition rate constants. White boxes correspond to non-force-bearing states. Gray boxes correspond to force-generating states. Transition from M⋅ATP to A⋅M⋅ADP⋅Pi is cooperatively facilitated by Ca²⁺ binding to troponin. See text for details.