Also see Figure S5 and Tables S2, S3. Top to bottom: Average proportions of cells with loss of membrane integrity, altered polarity, and high levels of activity across 3 unrelated individuals, determined after incubations with xenobiotics. Control incubations consisted of un-amended BHI medium, BHI medium with the drug vehicle (ethanol), and low pH. Treatments with a significant impact relative to controls are noted (p<0.05, Dunn’s test). Values are mean±sem.