Table 2.

Association of having diagnosis of both depression and anxiety on future diagnosis of dementia

Risk factor	Case n (%)	Control n (%)	Multivariable analysis. Odds ratio (95% CI)a
No anxiety or depression	258 (64.4)	1129 (93.4)	1.00
Anxiety alone	101 (25.3)	157 (11.6)	2.97 (2.21–4.00)
Depression alone	20 (5.0)	32 (2.4)	2.54 (1.39–4.63)
Anxiety and depression	21 (5.3)	35 (2.6)	2.85 (1.60–5.07)

^aMultivariable model controlling for age, gender, practice, year of case diagnosis of dementia and all risk factors and including interaction of anxiety with depression.