Table 3.
Association of depression and anxiety with diagnosis of dementia by gender
| Risk factor | Case n (%) | Control n (%) | Multivariable analysis. Odds ratio (95% CI)a |
|---|---|---|---|
| Female | |||
| No anxiety or depression | 152 (60.6) | 666 (79.9) | 1 |
| Anxiety alone | 73 (29.1) | 115 (13.8) | 1.71 (0.79–3.70) |
| Depression alone | 11 (4.4) | 26 (3.1) | 2.95 (2.07–4.22) |
| Anxiety and depression | 15 (6.0) | 27 (3.2) | 2.65 (1.35–5.23) |
| Male | |||
| No anxiety or depression | 106 (71.1) | 463 (89.2) | 1 |
| Anxiety alone | 28 (18.8) | 42 (8.1) | 3.12 (1.78–5.47) |
| Depression alone | 9 (6.0) | 6 (1.2) | 5.91 (1.98–17.6) |
| Anxiety and depression | 6 (4.0) | 8 (1.5) | 3.90 (1.21–12.57) |
aMultivariable model controlling for age, gender, practice, year of case diagnosis of dementia, and all risk factors and including interaction of anxiety with depression.