Table 1.
Demographic and Clinical Characteristics of Cases With Parkinson’s Disease (PD) and Control Subjects
| Case No. | Sex | Age at Death, y | Age at PD Onset, y | PD Duration, y | H&Y Stages | Motor UPDRS | Cause of Death | UPDRS Months Before Death | PMI (h) | Dysphagia |
|---|---|---|---|---|---|---|---|---|---|---|
| PD 1 | M | 75 | 55 | 20 | 2 | 17 | es-PD | 21 | 69 | Yes |
| PD 2 | M | 73 | 62 | 11 | 3 | 18 | es-PD | 26 | 26 | No |
| PD 3 | M | 78 | 59 | 19 | 4 | 51 | CAD | 8 | 76 | Yes |
| PD 4 | F | 84 | 64 | 20 | 3 | 29 | CPF | 10 | 48 | No |
| PD 5 | M | 80 | 69 | 11 | 4 | 53 | c-PD | 11 | 26 | No |
| PD 6 | M | 81 | 70 | 11 | 4 | 43 | es-PD | 19 | 58 | Yes |
| PD 7 | F | 79 | 68 | 11 | 4 | 47 | Pneu | 9 | 16 | No |
| PD 8 | M | 75 | 45 | 30 | 4 | 66 | es-PD | 1 | 36 | Yes |
| PD 9 | M | 80 | 63 | 17 | 5 | 40 | CPF | 5 | 23 | No |
| PD 10 | M | 79 | 56 | 23 | 2 | 28 | MNP | 9 | 34 | Yes |
| Mean (range) | 78 (73–84) | 61 (45–70) | 17 (11–30) | 3.5 (2–5) | 39 (17–66) | 12.0 (1–26) | 41 (16–76) | |||
| Control 1 | F | 74 | – | – | – | – | MSF | – | 24 | No |
| Control 2 | M | 80 | – | – | – | – | PC | – | 73 | No |
| Control 3 | M | 70 | – | – | – | – | stroke | – | 26 | No |
| Control 4 | F | 70 | – | – | – | – | CPF | – | 30 | No |
| Mean (range) | 73.5 (70–80) | 38 (24–73) |
CAD, coronary artery disease; c-PD, complications of PD; CPF, cardiopulmonary failure; es-PD, end stage of PD; F, female; H&Y, Hoehn-Yahr clinical rating scale (score range 1–5); M, male; MNP, malignant neoplasm of prostate; MSF, multisystem failure; PC, pancreatic cancer; PD, Parkinson’s disease; PMI, postmortem interval; Pneu, pneumonia; UPDRS, Unified Parkinson’s Disease Rating Scale.