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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2013 Feb;72(2):119–129. doi: 10.1097/NEN.0b013e3182801cde

Table 2.

Frequency and Severity of α-Synuclein Positive lesions in Cervical X Nerve and Ph-X in Subjects With Parkinson’s Disease

Case No. X nerve
Ph-X
LNs (range)    Severity of Lesions    LNs (range)    Severity of Lesions
1 26 (22–30)    ++    NA   
2 13 (10–14)    +    6 (3–10)    +
3 60 (42–69)    +++    24 (18–30)    ++
4 45 (33–56)    ++    22 (14–27)    ++
5 20 (14–26)    +    7 (3–11)    +
6 48 (35–57)    ++    21 (12–35)    ++
7 17 (12–24)    +    –    −
8 54 (39–62)    +++    23 (12–31)    ++
9 40 (21–55)    ++    10 (8–12)    +
10 55 (46–61)    +++    21 (13–26)    ++
Mean (range) 38 (13–60)       17 (6–24)   

The severity of α-synuclein positive lesions in the X nerve and Ph-X was rated according to the mean density of the LNs and assessed semiquantitatively following an arbitrary grading system: −, no lesions; +, 1–20 lesions/field (mild); ++, 21–50 lesions/field (moderate); +++, >50 lesions/field (severe). LNs, Lewy neurites; NA, not available.