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. 2013 Jan 10;137(3):903–913. doi: 10.1007/s10549-012-2400-2

Table 2.

Supplement use before and during breast cancer treatment

Supplement use before diagnosis Supplement use during treatment Total P a
No Yes
N (%) N (%) N (%)
Multivitamin
 No 510 (41.2) 133 (10.7) 643 (51.9) 0.0009
 Yes 193 (15.6) 402 (32.5) 595 (48.1)
 Total 703 (56.8) 535 (43.2) 1,238 (100)
Vitamin C
 No 931 (75.2) 62 (5.0) 993 (80.2) <.0001
 Yes 160 (12.9) 85 (6.9) 245 (19.8)
 Total 1,091 (88.1) 147 (11.9) 1,238 (100)
Vitamin D
 No 795 (64.2) 155 (12.5) 950 (76.7) 0.1229
 Yes 129 (10.4) 160 (12.9) 289 (23.3)
 Total 924 (74.6) 315 (25.4) 1,239 (100)
Vitamin E
 No 1,005 (81.2) 42 (3.4) 1,047 (84.6) <.0001
 Yes 154 (12.4) 37 (3.0) 191 (15.4)
 Total 1,159 (93.6) 79 (6.4) 1,238 (100)
Vitamin B6
 No 933 (75.4) 186 (15.0) 1,119 (90.4) <.0001
 Yes 69 (5.6) 50 (4.0) 119 (9.6)
 Total 1,002 (80.9) 236 (19.1) 1238 (100)
Folic Acid
 No 1,051 (84.8) 62 (5.0) 1,113 (89.8) 0.0231
 Yes 90 (7.3) 37 (3.0) 127 (10.2)
 Total 1,141 (92) 99 (8) 1,240 (100)
Vitamin B12
 No 999 (80.5) 82 (6.6) 1,081 (87.1) 0.2622
 Yes 97 (7.8) 63 (5.1) 160 (12.9)
 Total 1,096 (88.3) 145 (11.7) 1,241 (100)
Calcium
 No 695 (56.0) 119 (9.6) 814 (65.6) <.0001
 Yes 198 (16.0) 229 (18.4) 427 (34.4)
 Total 893 (72) 348 (28) 1,241 (100)
Fish oil, EPA, omega-3, flaxseed or cod liver oil
 No 907 (73.5) 47 (3.8) 954 (77.3) <.0001
 Yes 172 (13.9) 108 (8.8) 280 (22.7)
 Total 1,079 (87.4) 155 (12.6) 1,234 (100)
Glucosamine
 No 1,059 (85.7) 18 (1.5) 1,077 (87.1) <.0001
 Yes 97 (7.8) 62 (5.0) 159 (12.9)
 Total 1,156 (93.5) 80 (6.5) 1,236 (100)

aMcNemar’s test comparing the differences in use before and during treatment