Skip to main content
. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Nat Rev Immunol. 2012 May 11;12(6):443–458. doi: 10.1038/nri3212

Figure 4. General Overview of Promising Anti-GVHD Therapies.

Figure 4

The pathways inside the circle shows the most important pathophysiological pathways in the generation of aGVHD. The boxed outside the circle are some of the promising categories of therapeutic interventions and their most relevant immunological targets in GVHD. Plus signs represent the stimulatory effects and the minus signs represent the inhibitory effects of the therapeutics on a pathway.