Table 3.

Accuracy of APRI in predicting liver fibrosis

	APRI	All patients	Stage 0–2	Stage 3–4	Sensitivity	Specificity	PPV	NPV
HIV negative	≤0.5	38	37	1	0.96	0.46	0.35	0.97
	>0.5	68	44	24
	≤1.5	89	76	13	0.48	0.94	0.71	0.85
	>1.5	17	5	12
HIV positive	≤0.5	39	36	3	0.88	0.44	0.32	0.92
	>0.5	66	45	21
	≤1.5	92	75	17	0.29	0.93	0.54	0.82
	>1.5	13	6	7
CD4 ≤ 250	≤0.5	8	7	1	0.88	0.28	0.28	0.88
	>0.5	25	18	7
	≤1.5	28	21	6	0.25	0.88*	0.40	0.75
	>1.5	5	3	2
CD4 > 250	≤0.5	31	29	2	0.88	0.52	0.34	0.93
	>0.5	41	27	14
	≤1.5	64	53	11	0.31	0.95*	0.63	0.83
	>1.5	8	3	5

PPV, positive predictive value; NPV, negative predictive value.

^*Specificity in CD4 ≤ 250 cells/mm³ vs. CD4 > 250 cells/mm³, P = 0.05.