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. Author manuscript; available in PMC: 2013 Jan 23.
Published in final edited form as: Thromb Haemost. 2010 Sep 30;104(5):1044–1048. doi: 10.1160/TH09-08-0570

Figure 2.

Figure 2

FM19 inhibits α-thrombin-induced invasion through Matrigel in PC3 prostate cancer cells. PC3-luc cells were plated into the top well of an invasion chamber coated with Matrigel in the presence of 0–100 μM FM19 (A) or 0–10 μM bivalirudin (B). Cells were stimulated with 1 nM α-thrombin overnight. The data are represented as the number of cells per 100x field of view. In each experiment 10 fields of view were counted. Error bars represent the standard deviation from 3 independent experiments performed in the absence or presence of each concentration of each thrombin inhibitor.