. Author manuscript; available in PMC: 2013 Oct 25.

Published in final edited form as: Am J Nephrol. 2012 Oct 25;36(5):405–411. doi: 10.1159/000343495

Table 4. Longitudinal association between baseline measures of kidney function and change in telomere length over 5 years (from baseline to Y5)^* (N=608).

(Coefficients represent number of base pairs change associated with each unit of worsening kidney function; positive coefficient represents telomere lengthening; negative coefficient represents telomere shortening)

Measure of kidney function	Unadjusted β-coefficient (95% CI)	Adjusted for age β-coefficient (95% CI)
Serum creatinine (per 1 mg/dL increase)	−47.8^* (−93.3, −2.2)	−42.1 (−85.8, 1.7)
CrCl by 24 hour urine collection (per 5 ml/min decrease)	−3.6^* (−7.8, −0.1)	1.2 (−2.8, 5.1)
eGFR_CKD-EPI (per 5 ml/min/1.73 m² decrease)	−10.8^* (−17.3, −4.3)	−0.4 (−7.4, 6.7)
Log Cystatin C (per log mg/L increase)	−139.8^* (−231.1,−48.6)	−54.6 (−146.2, 37.1)
eGFRcys (per 5 ml/min/1.73 m² decrease)	−9.7^* (−15.5, −3.9)	−3.4 (−9.4, 2.5)
Log Urine albumin to creatinine ratio (per log mg/gram increase)	−6.9 (−28.5,14.7)	−5.4 (−26.1, 15.4)

P<0.05

Table 4. Longitudinal association between baseline measures of kidney function and change in telomere length over 5 years (from baseline to Y5)* (N=608).

Table 4. Longitudinal association between baseline measures of kidney function and change in telomere length over 5 years (from baseline to Y5)^* (N=608).