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Structure-based similarity among PET/MRI (frozen specimen), small-animal PET, and autoradiography images. 18F-FDG and 64Cu-antibody coregistered datasets were at whole-body and tumor ROI levels using SSIM (A and B) and CWSSIM (C and D). Pearson correlation coefficients comparing PET/MRI vs. autoradiography and small-animal PET vs. autoradiography metrics are shown.
