Table 1.

Frequency counts of samples in each class for marker pairs.

	Ei < Ej	Ei ≥ Ej	Total
Class C1	f11ij	f21ij	n1 = f11ij +f21ij
⋮	⋮	⋮	⋮
Class CM	f1Mij	f2Mij	nM =f1Mij +f2Mij
Total	$T_1={\Sigma }_{m=1}^M{f}_{1mij}$	$T_2={\Sigma }_{m=1}^M{f}_{2mij}$	N

The E_i and E_j represent the population of expression values for markers i and j respectively.

The n_i are the total number of samples in class C_i, i = 1,..., M.