Table 3.
Statistical analysis of haematological parameters for diagnosis of malarial infection
| Haematological parameter | Cases (n=335) | Control (n=100) | Sensitivity | Specificity | PPV | NPV | LR | 95%CI |
|---|---|---|---|---|---|---|---|---|
| Hb<12.5(g/dl) | 272 | 85 | 81.2 | 15 | 76.2 | 19.2 | 0.9 | 0.86–1.0 |
| TLC>11(×109/l) | 63 | 44 | 18.8 | 56 | 58.9 | 17.1 | 0.4 | 0.31–0.58 |
| TLC<4(×109/l) | 38 | 10 | 11.3 | 90 | 79.2 | 23.3 | 1.1 | 0.58–2.19 |
| RBC<4(×1012/l) | 190 | 63 | 56.7 | 37 | 75.1 | 20.3 | 0.9 | 0.75–1.07 |
| MCV80–100fl | 149 | 47 | 44.5 | 53 | 76 | 22.2 | 0.9 | 0.74–1.20 |
| RDW-CV >15 (%) | 140 | 52 | 41.8 | 48 | 72.9 | 19.8 | 0.8 | 0.64–1.00 |
| PC<150(×109/l) | 292 | 35 | 87.2 | 65 | 89.3 | 60.2 | 2.4 | 1.90–3.26 |
| PDW 6–10 | 241 | 67 | 71.9 | 33 | 78.2 | 26.0 | 2.0 | 1.56–2.70 |
| MPV<8fl | 130 | 41 | 38.8 | 59 | 76 | 22.3 | 0.9 | 0.72–1.24 |
| MPV>8fl | 205 | 59 | 61.5 | 41 | 77.7 | 56.6 | 1.03 | 0.86–1.24 |
PPV, Positive Predictive Value; NPV, Negative Predictive Value; LR, Likelihood Ratio; CI, Confidence Interval; TLC, Total Leukocyte Count; RBC, Red Blood Cell; MCV, Mean Corpuscular Volume; RDW-CV, Red Cell Distribution Width- Coefficient of Variation; PC, Platelet Count; MPV, Mean Platelet Volume; PDW, Platelet Distribution Width