Table 3.
Effects of rutin on renal antioxidant profile
| Treatment | CAT (U/min) | SOD (U/mg protein) | GSH-Px (nmol/mg protein) | GSR (nmol/min /mg protein) | GST (nmol/min/mg protein) |
|---|---|---|---|---|---|
| Control |
18.2±2.2++ |
19.05±1.54++ |
45.33±1.65++ |
203.3±10.3 ++ |
123.8±13.3++ |
| Saline (0.5 ml/kg bw; 0.9% NaCl) |
18.5±2.6++ |
19.75±1.4++ |
43.5±1.35++ |
200.6±8.3 ++ |
121.8±10.3++ |
| KBrO3 (20 mg/kg bw) |
7.5±0.85** |
7.58±2.08** |
23.35±3.08 ** |
114.5±20.7** |
53.8±26.1** |
| KBrO3+Rutin (50 mg/kg bw) |
11.5±2.2*++ |
12.83±1.87*++ |
34.91±5.54 *++ |
158.0±10.5*++ |
104.8±11.5 ++ |
| KBrO3+Rutin (70 mg/kg bw) |
16.5±2.6++ |
17.62±2.14++ |
41.26±4.6++ |
184.5±11.3++ |
116.5±14.3++ |
| Rutin alone (70 mg/kg bw) | 17.37±1.17++ | 20.72±1.72++ | 46.06±2.12++ | 207.3±13.2++ | 126.2±21.5++ |
Mean ± SEM (n=6 number).
*, ** indicate significance from the control group at P<0.05 and P<0.01 probability level.
++ indicate significance from the KBrO3 group P<0.01 probability level.