Table 4.
Effects of rutin on renal level of TBARS, GSH, AgNORs and DNA fragmentation
| Treatment | TBARS (nmol/min/mg protein) | GSH (μmol/g tissue) | DNA fragmentation% | AgNORs (NORs/cell) |
|---|---|---|---|---|
| Control |
8.17±0.93++ |
1.72±0.157++ |
7.75±0.834++ |
1.86±0.10++ |
| Saline (0.5 ml/kg bw; 0.9% NaCl) |
8.2±0.73++ |
1.68±0.17++ |
7.65±0.94++ |
1.81±0.12++ |
| KBrO3 (20 mg/kg bw) |
20.90±1.91** |
0.73±0.15** |
54.42±1.02** |
8.08±0.52** |
| KBrO3+Rutin (50 mg/kg bw) |
15.17±1.20++ |
1.28±0.19*++ |
27.85±1.26++ |
2.23±0.09++ |
| KBrO3+Rutin (70 mg/kg bw) |
10.25±1.35++ |
1.58±0.16++ |
9.25±1.35++ |
2.12±0.06++ |
| Rutin alone (70 mg/kg bw) | 9.17±1.06++ | 1.760±0.0817++ | 8.08±1.17++ | 1.95±0.13++ |
Mean ±SE M (n=6 number).
** indicate significance from the control group at P<0.01 probability level.
++ indicate significance from the KBrO3 group at P<0.01 probability level.