Figure 3. FANCD2 and BLM are present normally during MK endomitosis. (A) Western blot reveals BLM expression increased by proteasome inhibition. (B)I–III: BLM (green) localized to ultrafine anaphase bridges. IV–VI: FANCD2 (red) localized as spots on mitotic chromosomes. VII–IX: The arrow indicates one FANCD2 (green) spot on separating chromosomes during anaphase of endomitosis. (C) The arrow indicates a subset of BLM-stained bridges (green) connected to FANCD2 (red) spots on separating chromosome sets at anaphase. Bars, 10 μM.