Figure 1. Immunological alterations following FIV infection.

Cats in Group 1 were challenged with clonal GL8 (variant B32), cats in group 2 were challenged with the reconstituted quasispecies challenge (B14, B19, B28, B30, B31 and B32) and control cats remained unchallenged. Percentages of lymphocytes expressing (A) CD4 and (B) CD8 were measured by flow cytometry and are shown as group means +/− SE. (C) CD4:CD8 ratios were calculated from the percentage of CD4 and CD8 positive lymphocytes and are displayed as group means +/− SE. p-values for statistically significant differences between infected and control groups are shown (Student's t-test).