Table 4.
Serum biochemical values of animals treated with SST for 4 weeks
| Dose (mg/kg/day) | 0 | 500 | 1000 | 2000 |
|---|---|---|---|---|
|
Male rat |
|
|
|
|
| Glucose (mg/dL) |
120.0 ± 14.95 |
131.6 ± 18.66 |
133.8 ± 24.86 |
122.4 ± 6.90 |
| BUN (mg/dL) |
14.0 ± 1.58 |
13.5 ± 1.09 |
12.9 ± 1.90 |
12.9 ± 1.60 |
| Creatinine (mg/dL) |
0.57 ± 0.05 |
0.55 ± 0.05 |
0.55 ± 0.03 |
0.58 ± 0.04 |
| Total protein (g/dL) |
6.42 ± 0.13 |
6.54 ± 0.17 |
6.19 ± 0.29 |
6.48 ± 0.20 |
| Albumin (g/dL) |
4.08 ± 0.06 |
4.12 ± 0.12 |
3.99 ± 0.09 |
4.09 ± 0.09 |
| Albumin/globulin ratio |
1.75 ± 0.11 |
1.70 ± 0.08 |
1.83 ± 0.15 |
1.71 ± 0.05 |
| Total cholesterol (mg/dL) |
52.0 ± 7.75 |
57.0 ± 8.51 |
57.6 ± 18.77 |
50.8 ± 6.42 |
| Triglycerides (mg/dL) |
32.1 ± 9.98 |
31.4 ± 9.83 |
36.5 ± 8.41 |
36.0 ± 9.96 |
| Phospholipid (mg/dL) |
86 ± 10.0 |
90 ± 5.1 |
87 ± 19.6 |
87 ± 11.3 |
| AST (IU/L) |
136.1 ± 20.74 |
152.0 ± 33.87 |
119.8 ± 14.15 |
157.6 ± 32.13 |
| ALT (IU/L) |
28.4 ± 2.67 |
36.2 ± 11.11 |
30.5 ± 3.22 |
32.7 ± 2.25 |
| Total bilirubin (mg/dL) |
0.13 ± 0.010 |
0.13 ± 0.004 |
0.12 ± 0.015 |
0.113 ± 0.015 |
| ALP (IU/L) |
590.0 ± 84.05 |
506.1 ± 104.95 |
521.4 ± 94.21 |
557 ± 52.56 |
| Creatine kinase (IU/L) |
872 ± 275 |
935 ± 321 |
759 ± 156 |
989 ± 327 |
| Female |
|
|
|
|
| Glucose (mg/dL) |
100.3 ± 28.10 |
89.1 ± 18.43 |
98.9 ± 10.13 |
108.1 ± 18.59 |
| BUN (mg/dL) |
18.7 ± 1.87 |
17.7 ± 1.89 |
15.6 ± 2.22 |
15.3 ± 2.26 |
| Creatinine (mg/dL) |
0.62 ± 0.05 |
0.65 ± 0.05 |
0.58 ± 0.07 |
0.60 ± 0.03 |
| Total protein (g/dL) |
6.96 ± 0.11 |
6.94 ± 0.16 |
6.79 ± 0.14 |
6.98 ± 0.21 |
| Albumin (g/dL) |
4.47 ± 0.15 |
4.45 ± 0.09 |
4.34 ± 0.04 |
4.48 ± 0.10 |
| Albumin/globulin ratio |
1.79 ± 0.11 |
1.79 ± 0.08 |
1.78 ± 0.07 |
1.80 ± 0.13 |
| Total cholesterol (mg/dL) |
73.2 ± 14.96 |
65.6 ± 8.23 |
60.2 ± 7.36 |
56.0 ± 17.18 |
| Triglycerides (mg/dL) |
27.3 ± 3.67 |
25.6 ± 1.54 |
29.1 ± 7.61 |
25.2 ± 5.98 |
| Phospholipid (mg/dL) |
124 ± 19.4 |
111 ± 9.8 |
106 ± 11.6 |
104 ± 21.5 |
| ASP (IU/L) |
160.3 ± 25.73 |
142.6 ± 9.32 |
155.9 ± 27.99 |
140.9 ± 33.54 |
| ALT (IU/L) |
25.7 ± 2.47 |
30.0 ± 5.14 |
25.3 ± 3.46 |
26.7 ± 4.66 |
| Total bilirubin (mg/dL) |
0.13 ± 0.014 |
0.13 ± 0.014 |
0.12 ± 0.011 |
0.13 ± 0.010 |
| ALP (IU/L) |
413.6 ± 61.29 |
432.5 ± 86.29 |
379.4 ± 40.70 |
383.6 ± 103.75 |
| Creatine kinase (IU/L) | 1127 ± 288 | 966 ± 196 | 1044 ± 263 | 947 ± 411 |
ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alkaline phosphatase; BUN, blood urea nitrogen.
a Values are presented as mean ± SD.