Table 2.
Summary of total mutations detected by each histological classification
|
Histological classification |
Total microdissected targets tested |
Average number of mutated loci detected per microdissected target |
Average number of low/ligh clonality mutations detected per microdissected target |
Average mutational load |
|
|---|---|---|---|---|---|
| Low | High | ||||
| Normal Squamous |
82 |
0.1 |
0.1 |
0.0 |
0.1 |
| Columnar |
77 |
0.6 |
0.6 |
0.0 |
0.3 |
| Intestinal Metaplasia |
216 |
1.5 |
1.2 |
0.3 |
0.9 |
| Indefinite for dysplasia |
138 |
2.0 |
1.7 |
0.3 |
1.1 |
| Low grade dysplasia |
39 |
3.5 |
2.7 |
0.8 |
2.2 |
| High grade dysplasia | 16 | 4.0 | 1.5 | 2.5 | 3.3 |