Table 4.
Frequencies of mutational load (ML) in microdissected targets by histological classification
|
Histological classification of microdissected targets |
Level of Mutational load (ML) |
||
|---|---|---|---|
| No ML | Low ML (1 low clonality – 2 high clonality) | High ML (> 2 high clonality) | |
| Normal squamous |
74 (90%) |
8 (10%) |
0 (0%) |
| Columnar |
47 (61%) |
30 (39%) |
0 (0%) |
| Intestinal metaplasia |
48 (22%) |
159 (74%) |
9 (4%) |
| Indefinite for dysplasia |
20 (14%) |
106 (77%) |
12 (9%) |
| Low grade dysplasia |
0 (0%) |
22 (56%) |
17 (44%) |
| High grade dysplasia | 0 (0%) | 1 (6%) | 15 (94%) |