Figure 5. Comparison of the false negative rate for the four different methods.

Shown is the percentage of correctly recovered pathways (i.e. 1– false negative rate) as a function of the z-score. Solid lines represent internal crosstalk enrichment detection rates while dashed lines represent inter-crosstalk enrichment detection rates for KEGG pathways that were split into random halves. The test was performed using KEGG pathways mapped to the FunCoup network.