Figure 6. Representative examples of Focus Clear-enhanced visualization of the cerebral microvasculature.

(a) Depth-encoded MIP image of the brain slice in Figure 5 over the entire interrogation volume of 850 µm (b) Depth-encoded MIP image of a similar brain slice optically cleared with FocusClear from a different brain. Microvasculature is visualized to a depth of 820 µm in this slice.