Table 2. Gravimetric and echocardiographic data of PTX3-TG mice after TAC.

	Sham	TAC 4 weeks
Gravimetric data
BW (g)
WT	27.2±1.7	25.3±3.8*
PTX3-TG	28.0±1.8	24.2±2.5*
HW to BW ratio (mg/g)
WT	5.10±0.22	6.78±0.76**
PTX3-TG	5.07±0.31	8.03±1.68** #
LW to BW ratio (mg/g)
WT	5.21±0.61	6.22±0.73*
PTX3-TG	5.21±0.49	9.28±3.17** #
Echocardiographic data
Heart rate (beats/min)
WT	501±21.2	486±33.7
PTX3-TG	509±19.4	483±47.3
IVS (mm)
WT	0.67±0.05	1.00±0.18**
PTX3-TG	0.67±0.07	0.72±0.14##
LVEDD (mm)
WT	2.88±0.20	2.82±0.25
PTX3-TG	2.96±0.14	3.54±0.31##
LVFS (%)
WT	51.6±4.3	44.6±3.8**
PTX3-TG	51.7±4.6	35.5±2.7** ##

Abbreviations as in Table 1. PTX3-TG, PTX3 cardiac-specific overexpression mice. All data are shown as mean ± SD (n = 10 per group,).

^* P<0.05 and

^** P<0.01 vs. sham mice of the same strain;

^# P<0.05 and

^## P<0.01 vs. TAC-operated WT mice at each time point, respectively.