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. 2013 Jan 23;8(1):e54240. doi: 10.1371/journal.pone.0054240

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Note that miR -3065, -944 and -149-5p all were down-regulated and share multiple common targets (Panel A) and miR-192 and -215 all were up-regulated and share common targets (Panel B). These results of common targets for similarly up- or down- regulated miRNA suggest coordination between miRNA.