Table 5. Model evaluation.
Protein | ProQ_LG/MX | MetaMQAP_GDT/RMSD | DOPE Score | Z-Score |
IκBε | 3.518/0.242 | 48.092/4.089 | −22734.0566 | −7.0322 |
IκBNS | 5.228/0.325 | 59.684/2.725 | −25000.9805 | −9.9145 |
IκBζ | 4.617/0.312 | 49.060/4.155 | −25130.0215 | −7.0121 |
Relish | 4.050/0.220 | 51.914/4.056 | −23081.6074 | −7.9487 |
NF-κB1 | 4.832/0.322 | 50.800/3.693 | −24206.1484 | −9.7448 |
NF-κB2 | 5.029/0.299 | 55.449/2.885 | −23566.7383 | −9.3233 |
Cactus | 3.669/0.293 | 47.826/4.019 | −21998.7891 | −6.9505 |
The displayed IκB models are reliable in terms of overall packing. ProQ_LG: >1.5, fairly good; >2.5, very good; >4, extremely good. ProQ_MX: >0.l, fairly good; >0.5, very good; >0.8, extremely good. MetaMQAP_GDT/RMSD: an ideal model has a GDT score of >59 and an RMSD of ∼2.0 Å. Low DOPE scores indicate best model.