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. 2013 Jan 23;8(1):e54190. doi: 10.1371/journal.pone.0054190

Table 1. Characteristics of patients before and after intervention.

Variable Before, n = 71 After, n = 148 P
Age, mean years±SD (range) 62.0±10.6 (40–82) 59.0±17.0 (17–87) 0.86
Male sex 58 (81.7) 95 (64.2) <0.05
Malignant disease
Leukemia 27 (38.0) 78 (52.7) <0.05
Lymphoma 20 (28.2) 46 (31.1) 0.75
MDS 7 (9.9) 9 (6.1) 0.40
Multiple myeloma 17 (23.9) 7 (4.7) <0.01
Other 0 (0.0) 8 (5.4) 0.06
Therapy for hematological disorders
Chemotherapy 61 (85.9) 136 (91.9) 0.23
Autologous HSCT 9 (12.7) 8 (5.4) 0.10
Therapy for infectious diseases
Use of G-CSF 41 (57.7) 71 (48.0) 0.20
Use of Antimycotic drugs 54 (76.1) 84 (56.8) <0.01
Intravenous hyperalimentation catheter 49 (69.0) 115 (77.7) 0.19
Neutrophil cell count (/uL), mean 299.5±326.0 (0–968) 155.7±258.2(0–1270) <0.05
number ± SD (range)
MASCC score ± SD (range) 21.3±1.8 (16–24) 21.4±1.4 (17–23) 0.94

P-value shows statistical comparison for each variable between patients receiving pre-intervention and those receiving intervention.

MDS, myelodysplastic syndromes;HSCT, hematopoietic stem cell transplantation.

G-CSF, granulocyte colony-stimulating factor; MASCC, multinational association for supportive care in cancer.