Table 4. Antibiotic resistance of bacteremic isolates before and after intervention.

			CFPM-resistant
		Total No.	Rate (n) of isolates	Rate (n) of isolates	Rate (n) of isolates	Rate (n) of isolates	Rate (n) of isolates
Organism		of isolates	resistant to CFPM	producing ESBL	resistant to MEPM	resistant to PIPC/TAZ	resistant to CPFX
Gram-negative, total	Before	13	2.6 (6)a	1.7 (4)b	0.0 (0)	0.0 (0)	2.1 (5)c
	After	14	0.2 (1)a	0.0 (0)b	0.0 (0)	0.0 (0)	0.4 (2)c

Rate indicates number of positive cultures per 1000 patient days.

^a,b,c P-value shows statistical comparison for each variable between patients receiving pre-intervention and those receiving intervention.

^a p = 0.007,

^b p = 0.013,

^c p = 0.048.

CFPM, cefepime; ESBL, extended-spectrum β-lactamase; MEPM, meropenem; PIPC/TAZ, piperacillin-tazobactam; CPFX, ciprofloxacin.